Just before 10 p.m. on Sunday, officer responded to the 3100 block of Airport Way S. for the report of a man who had been shot multiple times.
Officers arrived on scene at the old Rainier Brewery, which has been converted to a multi-use building with private apartments inside.
Officer located the adult male victim on the sixth floor, but the suspects had already fled the scene.
The victim was taken to Harborview with life-threatening injuries.
The search for the suspects is ongoing. Police say they are unsure about what led up to the shooting.