It happened just before 3 a.m. Friday in the 5300 block of 4th Avenue South.
Police say a 1998 Ford Ranger pickup traveling northbound on the road collided with a 1997 Toyota Camry 4-door sedan for some unknown reason. The two vehicles collided head-on near South Bennett Street.
The driver of the Toyota, a male believed to be in his 20’s, was pronounced dead at the scene. The driver of the truck was transported to Harborview Medical Center with non-life threatening injuries.
Traffic investigators are investigating the crash.